- Mucinous adenocarcinoma is a pharmacogenomically distinct subtype of colorectal cancer. Reynolds IS, O’Connell E, Fichtner M, McNamara DA, Kay EW, Prehn JHM, Furney SJ, Burke JP. Pharmacogenomics J. 2019 Dec 10. doi: 10.1038/s41397-019-0137-6. [Epub ahead of print] PMID: 31819162
- Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment. Kenny A, McArdle H, Calero M, Rabano A, Madden SF, Adamson K, Forster R, Spain E, Prehn JHM, Henshall DC, Medina M, Jimenez-Mateos EM, Engel T. Biomolecules. 2019 Nov 13;9(11). pii: E734. doi: 10.3390/biom9110734. PMID: 31766231
- System-based approaches as prognostic tools for glioblastoma. Salvucci M, Zakaria Z, Carberry S, Tivnan A, Seifert V, Kögel D, Murphy BM, Prehn JHM. BMC Cancer. 2019 Nov 12;19(1):1092. doi: 10.1186/s12885-019-6280-2. Review. PMID: 31718568
- Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer’s disease. Kenny A, Jiménez-Mateos EM, Zea-Sevilla MA, Rábano A, Gili-Manzanaro P, Prehn JHM, Henshall DC, Ávila J, Engel T, Hernández F. Sci Rep. 2019 Oct 28;9(1):15437. doi: 10.1038/s41598-019-51837y. PMID:31659197
- Mucin Pools Following Neoadjuvant Chemoradiotherapy For Rectal Cancer: A Marker of Response or Epiphenomenon?Reynolds IS, O’Connell E, Fichtner M, Kay EW, McNamara DA, Prehn JHM, Burke JP. Am J Surg Pathol. 2019 Sep 17. doi: 10.1097/PAS.0000000000001373. [Epub ahead of print] PMID: 31567193
- The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia. Quinlan S, Merino-Serrais P, Di Grande A, Dussmann H, Prehn JHM, Ní Chonghaile T, Henshall DC, Jimenez-Mateos EM. Front Immunol. 2019 Jul 24;10:1752. doi: 10.3389/fimmu.2019.01752. eCollection 2019. PMID: 31396238
- Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model. Crivello M, Hogg MC, Jirström E, Halang L, Woods I, Rayner M, Coughlan KS, Lewandowski SA, Prehn JHM. Dis Model Mech. 2019 Aug 13;12(8). pii: dmm040238. doi: 10.1242/dmm.040238.PMID: 31383794
- The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia. Quinlan S, Merino-Serrais P, Di Grande A, Dussmann H, Prehn JHM, Ní Chonghaile T, Henshall DC, Jimenez-Mateos EM.Front Immunol. 2019 Jul 24;10:1752. doi: 10.3389/fimmu.2019.01752. eCollection 2019.PMID: 31396238
- Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer’s disease neurons. Theurey P, Connolly NMC, Fortunati I, Basso E, Lauwen S, Ferrante C, Moreira Pinho C, Joselin A, Gioran A, Bano D, Park DS, Ankarcrona M, Pizzo P,Prehn JHM. Aging Cell. 2019 Jun;18(3):e12924. doi: 10.1111/acel.12924. Epub 2019 Feb 21. PMID: 30793475
- Meta-analysis of the molecular associations of mucinous colorectal cancer. Reynolds IS, Furney SJ, Kay EW, McNamara DA,Prehn JHM, Burke JP. Br J Surg. 2019 May;106(6):682-691. doi: 10.1002/bjs.11142. Epub 2019 Apr 4. Review. PMID: 3094575Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression.Costard LS, Neubert V, Venø MT, Su J, Kjems J, Connolly NMC, Prehn JHM, Schratt G, Henshall DC, Rosenow F, Bauer S.Brain Stimul. 2019 Jun 7. pii: S1935-861X(19)30260-8. doi: 10.1016/j.brs.2019.06.009. [Epub ahead of print] PMID:31208877
- Context-Specific Switch from Anti- to Pro-epileptogenic Function of the P2Y1 Receptor in Experimental Epilepsy. Alves M, De Diego Garcia L, Conte G, Jimenez-Mateos EM, D’Orsi B, Sanz-Rodriguez A, Prehn JHM, Henshall DC, Engel T. J Neurosci. 2019 Jul 3;39(27):5377-5392. doi: 10.1523/JNEUROSCI.0089-19.2019. Epub 2019 May 2.PMID:31048325
- A Machine Learning Platform to Optimize the Translation of Personalized Network Models to the Clinic. Salvucci M, Rahman A, Resler AJ, Udupi GM, McNamara DA, Kay EW, Laurent-Puig P, Longley DB, Johnston PG, Lawler M, Wilson R, Salto-Tellez M, Van Schaeybroeck S, Rafferty M, Gallagher WM, Rehm M, Prehn JHM. JCO Clin Cancer Inform. 2019 Apr;3:1-17. doi: 10.1200/CCI.18.00056. PMID: 30995124
- Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer’s disease neurons. Theurey P, Connolly NMC, Fortunati I, Basso E, Lauwen S, Ferrante C, Moreira Pinho C, Joselin A, Gioran A, Bano D, Park DS, Ankarcrona M, Pizzo P, Prehn JHM.Aging Cell. 2019 Jun;18(3):e12924. doi: 10.1111/acel.12924. Epub 2019 Feb 21.
- Mucin glycoproteins block apoptosis; promote invasion, proliferation, and migration; and cause chemoresistance through diverse pathways in epithelial cancers. Reynolds IS, Fichtner M, McNamara DA, Kay EW, Prehn JHM, Burke JP. Cancer Metastasis Rev. 2019 Jan 24. doi: 10.1007/s10555-019-09781-w. [Epub ahead of print] Review. PMID:30680581
- Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre-Clinical Detection of Off-Target Toxicities Associated with Sunitinib Malate. O’Farrell AC, Miller IS, Evans R, Alamanou M, Cary M, Mallya Udupi G, Lafferty A, Monsefi N, Cremona M, Prehn JHM, Verheul HM, Gallagher WM, Gehrmann M, Byrne AT.Proteomics Clin Appl. 2019 Feb 15:e1800159. doi: 10.1002/prca.201800159.