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Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy. Ann Oncol. 2023 Mar;34(3):300-314. doi: 10.1016/j.annonc.2022.11.008. Epub 2022 Dec 6.PMID: 36494005
tRNA-derived fragments are altered in diabetes. Diabet Med. 2023 Nov 7:e15258. doi: 10.1111/dme.15258. Online ahead of print.PMID: 37935454
Ketone body β-hydroxybutyrate (BHB) preserves mitochondrial bioenergetics. Sci Rep. 2023 Nov 11;13(1):19664. doi: 10.1038/s41598-023-46776-8.PMID: 37952048
Chlorpromazine affects autophagy in association with altered Rag GTPase-mTORC1-TFEB signaling.
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Functional expression of the ATP-gated P2X7 receptor in human iPSC-derived astrocytes.
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Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
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Corrigendum: Mucinous adenocarcinoma of the rectum: a whole genome sequencing study.
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Bcl-xL Is a Key Mediator of Apoptosis Following KRASG12C Inhibition in KRASG12C-mutant Colorectal Cancer.
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Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors.
Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers. Br J Cancer. 2023 Oct;129(8):1327-1338. doi: 10.1038/s41416-023-02402-y. Epub 2023 Aug 24.PMID: 37620410
Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells. Int J Mol Sci. 2023 Oct 27;24(21):15678. doi: 10.3390/ijms242115678.PMID: 37958662
Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome. J Mol Med (Berl). 2023 Jul;101(7):829-841. doi: 10.1007/s00109-023-02324-5. Epub 2023 May 12.PMID: 37171483
Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders. Amyotroph Lateral Scler Frontotemporal Degener. 2023 Oct 1:1-15. doi: 10.1080/21678421.2023.2261979.
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Complexation of histone deacetylase inhibitor belinostat to Cu(II) prevents premature metabolic inactivation in vitro and demonstrates potent anti-cancer activity in vitro and ex vivo in colon cancer. Cell Oncol (Dordr). 2023 Nov 7. doi: 10.1007/s13402-023-00882-x. Online ahead of print.PMID: 37934338
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Desai S, Grefte S, van de Westerlo E, Lauwen S, Paters A, Prehn JHM, Gan Z, Keijer J, Adjobo-Hermans MJW, Koopman WJH.Biochim Biophys Acta Bioenerg. 2024 Apr 1;1865(2):149027. doi: 10.1016/j.bbabio.2023.149027. Epub 2023 Dec 17.PMID: 38109971