Functional expression of the ATP-gated P2X7 receptor in human iPSC-derived astrocytes.

Kesavan J, Watters O, de Diego-Garcia L, Méndez AM, Alves M, Dinkel K, Hamacher M, Prehn JHM, Henshall DC, Engel T.Purinergic Signal. 2024 Jun;20(3):303-309. doi: 10.1007/s11302-023-09957-8. Epub 2023 Jul 15.PMID: 37453017 

Integrative network analysis of miRNA-mRNA expression profiles during epileptogenesis in rats reveals therapeutic targets after emergence of first spontaneous seizure Khemka N, Morris G, Kazemzadeh L, Costard LS, Neubert V, Bauer S, Rosenow F, Venø MT, Kjems J, Henshall DC, Prehn JHM, Connolly NMC.Sci Rep. 2024 Jul 3;14(1):15313. doi: 10.1038/s41598-024-66117-7 PMID: 38961125

ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2-BECN1 interaction.

Xu S, Ma Q, Shen J, Li N, Sun S, Wang N, Chen Y, Dong C, Tam KY, Prehn JHM, Wang H, Ying Z.Acta Pharm Sin B. 2024 May;14(5):2026-2038. doi: 10.1016/j.apsb.2024.02.004. Epub 2024 Feb 7.PMID: 38799643

Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice.

Alves M, Gil B, Villegas-Salmerón J, Salari V, Martins-Ferreira R, Arribas Blázquez M, Menéndez Méndez A, Da Rosa Gerbatin R, Smith J, de Diego-Garcia L, Conte G, Sierra-Marquez J, Merino Serrais P, Mitra M, Fernandez Martin A, Wang Y, Kesavan J, Melia C, Parras A, Beamer E, Zimmer B, Heiland M, Cavanagh B, Parcianello Cipolat R, Morgan J, Teng X, Prehn JHM, Fabene PF, Bertini G, Artalejo AR, Ballestar E, Nicke A, Olivos-Oré LA, Connolly NMC, Henshall DC, Engel T.Brain Behav Immun. 2024 Aug;120:121-140. doi: 10.1016/j.bbi.2024.05.023. Epub 2024 May 20.PMID: 38777288 

Spatial transcriptomic analysis reveals local effects of intratumoral fusobacterial infection on DNA damage and immune signaling in rectal cancer.

Duggan WP, Kisakol B, Woods I, Azimi M, Dussmann H, Fay J, O’Grady T, Maguire B, Reynolds IS, Salvucci M, Slade DJ, McNamara DA, Burke JP, Prehn JHM.Gut Microbes. 2024 Jan-Dec;16(1):2350149. doi: 10.1080/19490976.2024.2350149. Epub 2024 May 6.PMID: 38709233  

Actin-nucleation promoting factor N-WASP influences alpha-synuclein condensates and pathology.

Jackson J, Hoffmann C, Scifo E, Wang H, Wischhof L, Piazzesi A, Mondal M, Shields H, Zhou X, Mondin M, Ryan EB, Döring H, Prehn JHM, Rottner K, Giannone G, Nicotera P, Ehninger D, Milovanovic D, Bano D.Cell Death Dis. 2024 Apr 30;15(4):304. doi: 10.1038/s41419-024-06686-7.PMID: 38693139 

Meta-analysis of SATB2 immunohistochemical expression in colorectal cancer versus primary ovarian mucinous neoplasms.

Maguire B, Duggan WP, Prehn JHM, Burke JP.Ann Diagn Pathol. 2024 Aug;71:152302. doi: 10.1016/j.anndiagpath.2024.152302. Epub 2024 Apr 16.PMID: 38642469

Identification of unique rectal cancer-specific subtypes.

Kisakol B, Matveeva A, Salvucci M, Kel A, McDonough E, Ginty F, Longley DB, Prehn JHM.Br J Cancer. 2024 May;130(11):1809-1818. doi: 10.1038/s41416-024-02656-0. Epub 2024 Mar 26.PMID: 38532103

Unlocking the secrets: exploring the influence of the aryl hydrocarbon receptor and microbiome on cancer development.

Rayan M, Sayed TS, Hussein OJ, Therachiyil L, Maayah ZH, Maccalli C, Uddin S, Prehn JHM, Korashy HM.Cell Mol Biol Lett. 2024 Mar 6;29(1):33. doi: 10.1186/s11658-024-00538-0.PMID: 38448800 

Spatial Effects of Infiltrating T cells on Neighbouring Cancer Cells and Prognosis in Stage III CRC patients.

Azimi M, Cho S, Bozkurt E, McDonough E, Kisakol B, Matveeva A, Salvucci M, Dussmann H, McDade S, Firat C, Urganci N, Shia J, Longley DB, Ginty F, Prehn JHM.bioRxiv [Preprint]. 2024 Mar 28:2024.01.30.577720. doi: 10.1101/2024.01.30.577720.Update in: J Pathol. 2024 Aug 2. doi: 10.1002/path.6327.PMID: 38352309 

Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle.

Sonsalla G, Malpartida AB, Riedemann T, Gusic M, Rusha E, Bulli G, Najas S, Janjic A, Hersbach BA, Smialowski P, Drukker M, Enard W, Prehn JHM, Prokisch H, Götz M, Masserdotti G.Neuron. 2024 Apr 3;112(7):1117-1132.e9. doi: 10.1016/j.neuron.2023.12.020. Epub 2024 Jan 23.PMID: 38266647

Share 

Performance of TMRM and Mitotrackers in mitochondrial morphofunctional analysis of primary human skin fibroblasts.

Desai S, Grefte S, van de Westerlo E, Lauwen S, Paters A, Prehn JHM, Gan Z, Keijer J, Adjobo-Hermans MJW, Koopman WJH.Biochim Biophys Acta Bioenerg. 2024 Apr 1;1865(2):149027. doi: 10.1016/j.bbabio.2023.149027. Epub 2023 Dec 17.PMID: 38109971

Share 

Complexation of histone deacetylase inhibitor belinostat to Cu(II) prevents premature metabolic inactivation in vitro and demonstrates potent anti-cancer activity in vitro and ex vivo in colon cancer.

Finnegan E, Ding W, Ude Z, Terer S, McGivern T, Blümel AM, Kirwan G, Shao X, Genua F, Yin X, Kel A, Fattah S, Myer PA, Cryan SA, Prehn JHM, O’Connor DP, Brennan L, Yochum G, Marmion CJ, Das S.Cell Oncol (Dordr). 2024 Apr;47(2):533-553. doi: 10.1007/s13402-023-00882-x. Epub 2023 Nov 7.PMID: 37934338